Zargis Cardioscan


Level 1 Diagnostics Zargis Cardioscan is the world’s first FDA-cleared medical device to identify and classify suspected heart murmurs. Zargis Cardioscan, HIPAA-compliant with a teleauscultation portal, has redefined what the stethoscope, the symbol of medicine, can do. Cardioscan connects wirelessly to the Bluetooth®-enabled 3M™ Littmann® Electronic Stethoscope Model 3200 for easy, real-time analysis. Using an electronic stethoscope connected to a portable computer, Cardioscan records and analyzes heart sounds, identifying suspected systolic and diastolic murmurs and S1 and S2 sounds, which are the potential signs of heart disease, and provides visual representations of the heart sound characteristics.

Zargis Cardioscan Process

Click Image To Enlarge

Zargis Cardioscan 2

Cardioscan guides you through a standard four-site cardiacauscultation exam. About a minute later, Cardioscan indicates whether or not the patient possesses a suspected diastolic or systolic murmur and whether or not they present a Class I indication for an echocardiography referral. The healthcare provider can view a full analysis of the heart sounds captured. When a suspected murmur is detected, Cardioscan indicates whether or not the sound meets the characteristics for classification as a Class I murmur according to the ACC/AHA recommendations for echocardiography in asymptomatic patients with cardiac murmurs.


  • Cardioscan follows the standard auscultation protocol and integrates seamlessly with clinical workflow.
  • Graphically displays shape and timing of suspected murmurs.
  • Store results on the PC or online for serial studies.
  • Review results when and where convenient and play recordings at slow speed to listen more closely.
  • Use Cardioscan’s display or printed results to better explain findings to patients, allay their anxiety or convince them of the need to follow through with additional care.
  • Cardioscan can also help document the complexity of auscultations. Automatically detects suspected systolic and diastolic heart murmurs and S1/S2 sounds.
  • Identifies suspected murmurs that have a Class I indication for echo referral per ACC/AHA guidelines.


Zargis Cardioscan was formed by Siemens AG (NYSE: SI), and Speedus Corp.(NASDAQ: SPDE) to develop and market computer-aided medical devices for use in diagnostic cardiac screening and telemedicine.

In 2006 Zargis received an award from The Wall Street Journal for Cardioscan as part of the Journal’s 2006 Technology Innovation Awards – annual competition honoring breakthrough technologies from around the world. The technology underlying the Cardioscan device was initially developed
within Siemens.

In 2005, in collaboration with The Johns Hopkins University School of Medicine, Zargis conducted a study to assess the impact of the Cardioscan system on referral decisions made by primary care physicians regarding heart murmurs. The results of the retrospective study, published in Clinical Cardiology in 2008, showed that Cardioscan lead to a 41% reduction of unnecessary and costly cardiac referrals by physicians. The study also credits Cardioscan with aiding physicians in improving detection of murmurs associated with potentially harmful heart disease by 46%. In 2009 3M Coporation obtained Zargis.

3M™ Littmann® Electronic Model 3200 Stethoscope


Clinical evidence shows it’s easier to detect difficult-to-hear heart sounds like S3 gallops, aortic regurgitation murmurs, as well as abnormal lung sounds with 3M™ Littman Electronic Stethoscope, compared to acoustic scopes. You can hear it, record it, send it, and it confirm it.

3M™ Littmann® Electronic Model 3200 Stethoscope Process

  • Easy to operate controls for power on/off, bell/ diaphragm/extended range frequency, and [+] and [-] buttons to adjust sound level up or down.
  • Convenient LCD Interface advises of current sound level in bell, diaphragm, or extended range frequency mode. Patient heart rate displays after just five seconds then updates every two seconds. A quick touch of the power button activates backlight for low-light conditions.
  • Auto-on feature means no waiting to start the next auscultation. Stethoscope stays in battery-saving “sleep mode” until the next auscultation is started.



  • State-of-the-art propriety ambient noise reduction technology sensor reduces on average 85% of unwanted background noise that can interfere with the auscultation experience, without eliminating critical body sounds.
  • Patented 3M™ Littmann® Snap Tight Soft-Sealing Ear tips provide a comfortable fit; they also create an excellent acoustic seal, as does the tubing.
  • Built to stringent specifications, it provides a life-like 3M™ Littmann® sound experience similar to a high-end cardiology stethoscope.
  • Extra listening power for those times when needed; may be helpful when a heart, lung or body sound is especially faint; when a patient is obese; or when a patient’s clothing restricts the listening experience one can amplify the sound up to 24X the normal condition.
  • About the same weight as a cardiology-grade acoustic stethoscope. Traditional tubing design drapes comfortably over the neck, and folds easily into a pocket.3M™ Littmann® patented softsealing ear tips in two sizes for a custom fit. Non-chill diaphragm for patient comfort.

Clinical Proof

With the Littmann® Model 3000 Series Stethoscope:

  • 83% of cardiologists indicated it was easier to detect/hear an S3 gallop
  • 82% of cardiologists indicated it was easier to detect/hear an aortic regurgitation murmur (Grade 1 or 2)
  • 90% of critical care nurses indicated it was easier to detect/hear abnormal lung sounds.